Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length122 amino acids

Chemical FormulaC572H924N164O188S9

DescriptionStandard

        MKPLLLALSMLVLLPQVIPAYSGEKKCWNKSGHCRKQCKDGEAVRETCKNLRACCVPSNEDHRQIPTTSSTPLNDSSPGIMDDVATIRFTTDYFEVSSKKDLAEESESGGTQTSLPNVHHSS
    

Molecular Weight13395.03 Da

Isoelectric Point (pI)6.40

Net Charge (pH 7.0)-1.19

Net Charge (pH 7.4) -1.73

Charge Density (pH 7.0) -0.0098

GRAVY Index-0.53

Hydrophobic Moment 0.72

Boman Index-0.09

Instability Index48.28

Aliphatic Index 69.51

Aromaticity 0.0410

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5661.58

LogP -69.42

H-bond Donors 200.0

H-bond Acceptors 200.0

Rotatable Bonds 445.0

Heavy Atoms 933.0

Ring Count 18.0

Amide Bonds 130.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0172546 VERIFIED: NO

Provenance & Taxonomy

OrganismCebus imitator [Animal]

FamilyBeta-defensin; Defensin

Tax ID9516

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic