Peptide Database

Peptide NameJ18 (galanin analogue)

Function Ontology

Neurological / Signaling ▸ Neuropeptide activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC105H174N34O27

DescriptionStandard

        RGRGNWTLNSAGYLLGPKKKK
    

Molecular Weight2344.72 Da

Isoelectric Point (pI)11.22

Net Charge (pH 7.0)5.76

Net Charge (pH 7.4) 5.54

Charge Density (pH 7.0) 0.2741

GRAVY Index-1.20

Hydrophobic Moment 0.27

Boman Index-0.28

Instability Index-18.74

Aliphatic Index 60.48

Aromaticity 0.0952

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1027.07

LogP -10.88

H-bond Donors 37.0

H-bond Acceptors 33.0

Rotatable Bonds 80.0

Heavy Atoms 166.0

Ring Count 4.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0268445 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor agonist Neuropeptide activity Signaling peptide

TargetGAL1 receptor (Human); GAL2 receptor (Human); GAL3 receptor (Human)

Activity138 nM

MethodKi