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MYP_160422
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Basic Information
Salivaricin B
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
25 amino acids
C120H182N34O36S4
Standard
Sequence
GGGVIQTISHECRMNSWQFLFTCCS
Physicochemical Analysis
2805.19 Da
6.72
-0.18
-0.48
-0.0072
0.18
0.52
0.17
34.03
58.40
0.1200
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1135.81
-13.29
43.0
41.0
90.0
194.0
5.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0072222 VERIFIED: NO
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]; Bacteria [Bacterium]
2; 2
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0091898 VERIFIED: YES
Provenance & Taxonomy
Streptococcus salivarius K12 [Bacterium]
Bacteriocin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
PMID17194838 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17194838/
RECORD: Rec_0127229 VERIFIED: YES
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0134224 VERIFIED: YES
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Three thioether bonds are predicted between 7,12; 9,23; and 16,24
Bio-Activity Profile
Antimicrobial
9 indicator strains such as S. salivarius K12, S. salivarius 20P3
PaperSalivaricin A2 and the novel lantibiotic salivaricin B are encoded at adjacent loci on a 190-kilobase transmissible megaplasmid in the oral probiotic strain Streptococcus salivarius K12
RECORD: Rec_0279611 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 16.0%, E 0.0%, T 36.0%, C 48.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Anti-Gram-positive
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
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