Peptide Database

Peptide NameNeutrophil antibiotic peptide NP-1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length96 amino acids

Chemical FormulaC466H760N142O142S7

DescriptionStandard

        MRTLFLLIALPLLALQTQAEPPLGRAEEVLDQEQLGEDEQGVSIFLGGDDSTALQDADVRSGVTCYCRRGGCRFPERLLGYCRDRRNIVYRLCCRR
    

Molecular Weight10848.34 Da

Isoelectric Point (pI)5.40

Net Charge (pH 7.0)-1.53

Net Charge (pH 7.4) -1.86

Charge Density (pH 7.0) -0.0160

GRAVY Index-0.24

Hydrophobic Moment 0.81

Boman Index-0.11

Instability Index62.76

Aliphatic Index 94.48

Aromaticity 0.0625

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4623.49

LogP -46.94

H-bond Donors 169.0

H-bond Acceptors 148.0

Rotatable Bonds 363.0

Heavy Atoms 757.0

Ring Count 10.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0187081 VERIFIED: NO

Provenance & Taxonomy

OrganismMicrotus ochrogaster [Animal]

FamilyDefensin

Tax ID79684

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal