Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length99 amino acids

Chemical FormulaC484H722N146O147S10

DescriptionStandard

        EEAHPYLSECCSYSLQPSHHLHPGSCRHEAGSPASCHICDNGTGNVRGFCRPSCKKGEQAYFYCRTYQICCLQSHVRISLTGVEDNTNWSYEKHWPRIP
    

Molecular Weight11258.45 Da

Isoelectric Point (pI)7.23

Net Charge (pH 7.0)0.45

Net Charge (pH 7.4) -0.30

Charge Density (pH 7.0) 0.0045

GRAVY Index-0.72

Hydrophobic Moment 0.61

Boman Index-0.09

Instability Index61.00

Aliphatic Index 48.28

Aromaticity 0.1010

Extinction Coeff. Reduced 19940.00

Extinction Coeff. Oxidized 20565.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4669.32

LogP -55.05

H-bond Donors 172.0

H-bond Acceptors 165.0

Rotatable Bonds 353.0

Heavy Atoms 787.0

Ring Count 27.0

Amide Bonds 106.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0393817 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyDefensin

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence