Peptide Database

Peptide NameHuman granulysin

Function Ontology

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Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC118H205N35O34S2

DescriptionStandard

        GRDYRTCLTIVQKLKKMVDKPTQ
    

Molecular Weight2722.23 Da

Isoelectric Point (pI)9.86

Net Charge (pH 7.0)3.75

Net Charge (pH 7.4) 3.52

Charge Density (pH 7.0) 0.1629

GRAVY Index-0.83

Hydrophobic Moment 0.73

Boman Index-0.32

Instability Index-3.10

Aliphatic Index 76.09

Aromaticity 0.0435

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1164.31

LogP -11.05

H-bond Donors 42.0

H-bond Acceptors 40.0

Rotatable Bonds 95.0

Heavy Atoms 189.0

Ring Count 2.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0277224 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)