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MYP_160322
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Basic Information
eCATH-1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Standard
26 amino acids
C144H255N47O29S
Standard
Sequence
KRFGRLAKSFLRMRILLPRRKILLAS
Physicochemical Analysis
3140.93 Da
12.00
8.76
8.55
0.3368
0.02
0.95
-0.23
64.75
127.69
0.0769
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1271.95
-7.75
49.0
39.0
111.0
221.0
3.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0090051 VERIFIED: YES
Provenance & Taxonomy
Equus asinus [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiparasitic
a broad range of bacteria Escherichia coli ATCC 25922 or ML 35
3 μg/mL
MIC
PaperNovel cathelicidins in horse leukocytes.
RECORD: Rec_0095517 VERIFIED: YES
Provenance & Taxonomy
Equus caballus [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0102555 VERIFIED: NO
Provenance & Taxonomy
Equus caballus [Animal]
cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperMyeloid cathelicidin 1 Evidence URLhttps://www.uniprot.org/uniprotkb/O62840/entry
RECORD: Rec_0119210 VERIFIED: YES
Provenance & Taxonomy
Equus asinus [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiparasitic
C.parapsilosis
>100 μg/mL
MIC
PaperNovel cathelicidins in horse leukocytes.
RECORD: Rec_0122585 VERIFIED: YES
Provenance & Taxonomy
Equus asinus [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiparasitic
S. marcescens ATCC 8100
12.5 μg/mL
MIC
PaperNovel cathelicidins in horse leukocytes.
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