Peptide Database

Peptide NameDefensin beta 1 (beta-defensin 1)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC332H505N87O87S10

DescriptionStandard

        MKTHCFLLLMFCFLFFQIAPGAGLTSLGHRSDHYLCVKNGGFCLYSSCPLHTKVEGTCYQGKGNCCK
    

Molecular Weight7427.74 Da

Isoelectric Point (pI)8.69

Net Charge (pH 7.0)3.77

Net Charge (pH 7.4) 3.22

Charge Density (pH 7.0) 0.0562

GRAVY Index0.26

Hydrophobic Moment 0.35

Boman Index0.19

Instability Index28.22

Aliphatic Index 69.85

Aromaticity 0.1343

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2742.55

LogP -24.60

H-bond Donors 103.0

H-bond Acceptors 105.0

Rotatable Bonds 240.0

Heavy Atoms 516.0

Ring Count 15.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0358052 VERIFIED: NO

Provenance & Taxonomy

OrganismCastor canadensis [Animal]

FamilyDefensin

Tax ID51338

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal