Peptide Database

Peptide NameEndolysin (EC 4.2.2.n2) (Lysis protein) (Lysozyme) (Transglycosylase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Lyase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length162 amino acids

Chemical FormulaC809H1280N226O238S6

DescriptionStandard

        MKLDKNVQRKAFLDMIAYSEGTDNGRQPTNDRGYDVIVGGKLFSDYSKHPGVYVKLNAKLTSSAAGRYQILEKFAKHYMKQLGLPDFGPASQDKIALQLIRECKALDDIDEGRIHQAIYKCRSRWASFPPPPGAGKLYNQRAESIDKMLDIFKKSGGVVTDE
    

Molecular Weight18172.58 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)5.75

Net Charge (pH 7.4) 5.30

Charge Density (pH 7.0) 0.0355

GRAVY Index-0.59

Hydrophobic Moment 0.68

Boman Index-0.09

Instability Index35.10

Aliphatic Index 75.93

Aromaticity 0.0926

Extinction Coeff. Reduced 17420.00

Extinction Coeff. Oxidized 17545.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7530.60

LogP -72.87

H-bond Donors 260.0

H-bond Acceptors 253.0

Rotatable Bonds 616.0

Heavy Atoms 1279.0

Ring Count 27.0

Amide Bonds 174.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0030424 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia phage FV3 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Lyase Cytolytic Non-hemolytic