MYP_160202
Lactacystin
Antimicrobial
Antiparasitic
▸
Antimalarial
Antiparasitic
▸
General antiparasitic
▸
Antiparasitic
Enzyme modulation
▸
Enzyme inhibition
▸
Proteasome inhibitor
not Standard
27 amino acids
-
contains X representing unresolved or non-standard residue
SXXXHYDRXXYHYDRXXYXCYSTEINE
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0066866
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protease/Proteasome inhibitor
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Acetylation
None
Bio-Activity Profile
Antimicrobial
Proteasome inhibitor
Antiparasitic
Antimalarial
Plasmodium falciparum 3D7
1.49 μM
IC50; ELISA (HRP-II levels detection)
RECORD: Rec_0109286
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protease/Proteasome inhibitor
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Acetylation
None
Bio-Activity Profile
Antimicrobial
Proteasome inhibitor
Antiparasitic
Antimalarial
Plasmodium falciparum D10
1.211 μM
IC50; ELISA (HRP-II levels detection)
RECORD: Rec_0316050
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protease/Proteasome inhibitor
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Acetylation
None
Bio-Activity Profile
Antimicrobial
Proteasome inhibitor
Antiparasitic
Antimalarial
Plasmodium falciparum Dd2
2.553 μM
IC50; ELISA (HRP-II levels detection)