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MYP_160194
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Basic Information
CRAMP-18[Q9K]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
18 amino acids
C102H175N27O23
Standard
Sequence
GEKLKKIGKKIKNFFQKL
Physicochemical Analysis
2147.65 Da
10.40
5.76
5.54
0.3198
-0.91
0.82
-0.26
-36.11
86.67
0.1111
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
863.64
-4.52
29.0
29.0
83.0
152.0
2.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0010400 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
μM
100 μM
Hemolysis
PMID10973820 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10973820/
RECORD: Rec_0020139 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: Jurkat
66 μM
IC50
PMID10973820 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10973820/
RECORD: Rec_0101702 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Human erythrocytes
100 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/10973820/ PMID10973820 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10973820/
RECORD: Rec_0210613 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
K562
85 μM
IC50
PMID10973820 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10973820/
RECORD: Rec_0221473 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
PMID10973820 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10973820/
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