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MYP_160183
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Basic Information
SA-hepcidin2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiviral
Standard
24 amino acids
C99H156N32O27S9
Standard
Sequence
NPAGCRFCCGCCPNMIGCGVCCRF
Physicochemical Analysis
2515.08 Da
8.23
1.68
1.36
0.0700
0.72
0.33
0.17
24.43
32.50
0.0833
0.00
500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
925.02
-12.24
39.0
38.0
75.0
167.0
4.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0128666 VERIFIED: NO
Provenance & Taxonomy
Scatophagus argus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral
Siniperca chuatsi rhabdovirus, Micropterus salmoides reovirus
RECORD: Rec_0160443 VERIFIED: YES
Provenance & Taxonomy
Scatophagus argus [Animal]
Hepcidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral Anti-Gram-positive Anti-Gram-negative
Vibrio anguillarum
50 μM
MIC
PMID26845697 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26845697/
RECORD: Rec_0211635 VERIFIED: YES
Provenance & Taxonomy
Scatophagus argus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0216622 VERIFIED: YES
Provenance & Taxonomy
Scatophagus argus [Animal]
Hepcidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
50 μM
MIC
PMID26845697 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26845697/
RECORD: Rec_0217775 VERIFIED: YES
Provenance & Taxonomy
Scatophagus argus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
V-fluvialis
>50 μM
MIC
PaperTwo hepcidins from spotted scat (Scatophagus argus) possess antibacterial and antiviral functions in vitro
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