Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length419 amino acids

Chemical FormulaC2097H3377N547O588S15

DescriptionStandard

        MFLCGWLVMVTLIPVILSVNPGVEVKITDKGIEYGRQLGIAAIQEKLKKIRIPDFSGKQRVSPIGKVQYSLTNIQIVNIGLPIAPIQLVPGSGVKLSINNAFINLRGNWRVKFLRWVKNSGSFEVGMNDLSISESLAVKSDSTGRPEVSTISCAASVGRVRIKFHGGASWLYNLFSKYIEKALKSALQKQICPLVTNAIDDMNPRLKTLNVLANVDKYAEIEYSMVSSPAISSSSIALKLKGQFYNIGQHQEPPFSAPAFSLPPENSNMLYMALSAFTANSAAFVYHKAGVLSIYITDDMIPKRSPIRLTTTTFGTFIPQISKQFPGLMMKLLMKTDKSPVVTFEPDRVTVQVTGTVTAYAIQPNDTLTPLFILNLVGNAISIQRLGIQLGKGYPLPAIRNMELENTKLQILKVRDELF
    

Molecular Weight46140.53 Da

Isoelectric Point (pI)9.69

Net Charge (pH 7.0)16.75

Net Charge (pH 7.4) 16.24

Charge Density (pH 7.0) 0.0400

GRAVY Index0.12

Hydrophobic Moment 0.72

Boman Index0.13

Instability Index37.60

Aliphatic Index 104.92

Aromaticity 0.0811

Extinction Coeff. Reduced 39880.00

Extinction Coeff. Oxidized 40005.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0264473 VERIFIED: NO

Provenance & Taxonomy

OrganismTakifugu rubripes (Japanese pufferfish) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria