Peptide Database

Peptide Name[D-Lys18] Ascaphin-8

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC97H164N24O23

DescriptionStandard

        GFKDLLKGAAKALVKTVKF
    

Molecular Weight2034.49 Da

Isoelectric Point (pI)10.18

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.1977

GRAVY Index0.33

Hydrophobic Moment 0.68

Boman Index0.11

Instability Index-14.87

Aliphatic Index 107.89

Aromaticity 0.1053

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 774.75

LogP -4.12

H-bond Donors 27.0

H-bond Acceptors 27.0

Rotatable Bonds 72.0

Heavy Atoms 144.0

Ring Count 2.0

Amide Bonds 18.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0309447 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyAscaphin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetCandida albicans ATCC 900280

Activity12 μM

MethodMIC

RECORD: Rec_0376725 VERIFIED: YES