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MYP_160110
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Basic Information
[D-Lys18] Ascaphin-8
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
19 amino acids
C97H164N24O23
Standard
Sequence
GFKDLLKGAAKALVKTVKF
Physicochemical Analysis
2034.49 Da
10.18
3.76
3.55
0.1977
0.33
0.68
0.11
-14.87
107.89
0.1053
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
774.75
-4.12
27.0
27.0
72.0
144.0
2.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0011581 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: HepG2
140 μM
LC50
PMID18554256 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18554256/
RECORD: Rec_0039570 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: HepG2
200 μM
LC50
PMID18554256 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18554256/
RECORD: Rec_0096444 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
fibroblast-derived cells
55 μM
LC50
PMID18554256 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18554256/
RECORD: Rec_0110791 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
500 μM
LC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/18554256/ PMID18554256 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18554256/
RECORD: Rec_0130865 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Ascaphin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
>500 μM
HC50
PMID18554256 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18554256/
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