Peptide Database

Peptide NameSLAY-screened peptide P43

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC73H122N18O22

DescriptionStandard

        LYAEVGRLLIDLGAT
    

Molecular Weight1603.86 Da

Isoelectric Point (pI)4.37

Net Charge (pH 7.0)-1.24

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.0825

GRAVY Index0.88

Hydrophobic Moment 0.55

Boman Index0.33

Instability Index13.80

Aliphatic Index 162.67

Aromaticity 0.0667

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 647.68

LogP -3.69

H-bond Donors 23.0

H-bond Acceptors 21.0

Rotatable Bonds 52.0

Heavy Atoms 113.0

Ring Count 1.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0242781 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/