Peptide Database

Peptide NameSLAY-screened peptide P1006

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC91H156N28O27S3

DescriptionStandard

        LLIHLCRCPNLCSLVSGNNT
    

Molecular Weight2170.58 Da

Isoelectric Point (pI)7.98

Net Charge (pH 7.0)0.82

Net Charge (pH 7.4) 0.52

Charge Density (pH 7.0) 0.0409

GRAVY Index0.64

Hydrophobic Moment 0.35

Boman Index0.18

Instability Index16.81

Aliphatic Index 131.50

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 887.97

LogP -10.31

H-bond Donors 33.0

H-bond Acceptors 32.0

Rotatable Bonds 69.0

Heavy Atoms 149.0

Ring Count 2.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0041586 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/