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MYP_159909
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Basic Information
MCF
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
15 amino acids
C82H140N26O19
Standard
Sequence
GLPALISWIKRKRQQ
Physicochemical Analysis
1794.15 Da
12.00
3.76
3.55
0.2505
-0.61
0.57
-0.20
98.50
110.67
0.0667
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
759.97
-5.44
27.0
23.0
61.0
127.0
3.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0097403 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Bacillus subtilis
15-25 μg/mL
MIC
PaperBiological activities of C-terminal 15-residue synthetic fragment of melittin: design of an analog with improved antibacterial activity
RECORD: Rec_0105945 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus 8530B
25-35 μg/mL
MIC
PaperBiological activities of C-terminal 15-residue synthetic fragment of melittin: design of an analog with improved antibacterial activity
RECORD: Rec_0147304 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 53.3%, E 0.0%, T 20.0%, C 26.7% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0156255 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Toxicity
HC50 reached 100 ug/ml comapred to the parent peptide
<1 μg/mL
HC50
PaperBiological activities of C-terminal 15-residue synthetic fragment of melittin: design of an analog with improved antibacterial activity
RECORD: Rec_0289457 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
P.putida NCIM 2102
>200 μg/mL
MIC
PaperBiological activities of C-terminal 15-residue synthetic fragment of melittin: design of an analog with improved antibacterial activity
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