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MYP_159909
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Basic Information
MCF
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
15 amino acids
C82H140N26O19
Standard
Sequence
GLPALISWIKRKRQQ
Physicochemical Analysis
1794.15 Da
12.00
3.76
3.55
0.2505
-0.61
0.57
-0.20
98.50
110.67
0.0667
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
759.97
-5.44
27.0
23.0
61.0
127.0
3.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0025608 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli W 160-37
35-45 μg/mL
MIC
PaperBiological activities of C-terminal 15-residue synthetic fragment of melittin: design of an analog with improved antibacterial activity
RECORD: Rec_0042992 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Human erythrocytes
4500 μg/mL
Paperhttps://pubmed.ncbi.nlm.nih.gov/14596922/ PMID14596922 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14596922/
RECORD: Rec_0051473 VERIFIED: YES
Provenance & Taxonomy
Apis mellifera [Animal]
Melittin
7460
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
5.6 μg/mL
MIC
PMID14596922 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14596922/
RECORD: Rec_0053499 VERIFIED: YES
Provenance & Taxonomy
Apis mellifera [Animal]
Melittin
7460
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
human erythrocytes
4500 μg/mL
Hemolysis
PMID14596922 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14596922/
RECORD: Rec_0076856 VERIFIED: YES
Provenance & Taxonomy
Apis mellifera [Animal]
Melittin
7460
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
5.6 μg/mL
MIC
PMID14596922 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14596922/
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