Peptide Database

Peptide NameKnot1 domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length80 amino acids

Chemical FormulaC397H587N101O111S10

DescriptionStandard

        MAKFASIIAFLFAALVLFASFEAPTMVEAQKYCEKPSGTWSGVCGNSNACNNQCINLEGARHGSCNYVFPYYRCICYFQC
    

Molecular Weight8871.17 Da

Isoelectric Point (pI)7.50

Net Charge (pH 7.0)0.51

Net Charge (pH 7.4) 0.11

Charge Density (pH 7.0) 0.0064

GRAVY Index0.27

Hydrophobic Moment 0.48

Boman Index0.20

Instability Index19.91

Aliphatic Index 66.00

Aromaticity 0.1625

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3382.18

LogP -32.22

H-bond Donors 123.0

H-bond Acceptors 123.0

Rotatable Bonds 279.0

Heavy Atoms 619.0

Ring Count 18.0

Amide Bonds 88.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0383200 VERIFIED: NO

Provenance & Taxonomy

OrganismArabis alpina [Plant]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence