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MYP_159825
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Basic Information
Astacidin PcAst-1b/c
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
23 amino acids
C132H202N42O30
Standard
Sequence
SNVYRPPPYRPVYRPLRRPGYRP
Physicochemical Analysis
2857.28 Da
11.38
5.46
5.24
0.2372
-1.56
0.93
-0.46
70.18
42.17
0.1739
5960.00
5960.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1157.63
-9.16
41.0
36.0
77.0
204.0
11.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0000204 VERIFIED: YES
Provenance & Taxonomy
Procambarus clarkii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumannii c.i.
2 μM
MIC
PMID31884202 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31884202/
RECORD: Rec_0037337 VERIFIED: YES
Provenance & Taxonomy
Procambarus clarkii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC c.i.
32 μM
MIC
PMID31884202 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31884202/
RECORD: Rec_0087361 VERIFIED: YES
Provenance & Taxonomy
Procambarus clarkii,Procambarus clarkii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
T24
100 μM
IC50
PaperPubMed PMID: 31884202 PMID31884202 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31884202/
RECORD: Rec_0158176 VERIFIED: YES
Provenance & Taxonomy
Procambarus clarkii,Procambarus clarkii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
MEC-1 (Not active up to 100 μM)
PaperPubMed PMID: 31884202 PMID31884202 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31884202/
RECORD: Rec_0230391 VERIFIED: YES
Provenance & Taxonomy
Procambarus clarkii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer Anti-Gram-positive Anti-Gram-negative
Escherichia coli c.i
2 μM
MIC
PMID31884202 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31884202/
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