Peptide Database

Peptide NameSLAY-screened peptide P3851

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC72H123N25O16

DescriptionStandard

        RKLRLYHPVGVTR
    

Molecular Weight1594.90 Da

Isoelectric Point (pI)11.72

Net Charge (pH 7.0)3.85

Net Charge (pH 7.4) 3.59

Charge Density (pH 7.0) 0.2958

GRAVY Index-0.66

Hydrophobic Moment 0.36

Boman Index-0.34

Instability Index26.55

Aliphatic Index 104.62

Aromaticity 0.0769

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 684.59

LogP -5.03

H-bond Donors 26.0

H-bond Acceptors 21.0

Rotatable Bonds 51.0

Heavy Atoms 113.0

Ring Count 3.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0016984 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/