Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC474H783N121O134S8

DescriptionStandard

        MKLFLILIILLFEVSEDSARSRKCFSTIAGYCKKKCMLGEIYDKPCTKGKLCCINESKKKTHQQAVQQPEPASKPDLKLDYVILPTVTLGTIPQ
    

Molecular Weight10577.54 Da

Isoelectric Point (pI)9.08

Net Charge (pH 7.0)5.53

Net Charge (pH 7.4) 5.14

Charge Density (pH 7.0) 0.0588

GRAVY Index-0.11

Hydrophobic Moment 0.51

Boman Index0.01

Instability Index45.31

Aliphatic Index 95.43

Aromaticity 0.0638

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4105.31

LogP -33.88

H-bond Donors 145.0

H-bond Acceptors 149.0

Rotatable Bonds 361.0

Heavy Atoms 737.0

Ring Count 13.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0243894 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Tax ID9913

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence