Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length69 amino acids

Chemical FormulaC342H563N85O86S2

DescriptionStandard

        MELDLAVTIGLPALIARRVVNLVLAGASFWSIMSLIIAGGGIVGIGIASLIYLVKRKLKEWTADAVVAW
    

Molecular Weight7305.78 Da

Isoelectric Point (pI)9.52

Net Charge (pH 7.0)1.50

Net Charge (pH 7.4) 1.28

Charge Density (pH 7.0) 0.0218

GRAVY Index1.17

Hydrophobic Moment 0.60

Boman Index0.43

Instability Index21.33

Aliphatic Index 155.51

Aromaticity 0.0725

Extinction Coeff. Reduced 17990.00

Extinction Coeff. Oxidized 17990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2678.36

LogP -13.06

H-bond Donors 96.0

H-bond Acceptors 90.0

Rotatable Bonds 240.0

Heavy Atoms 515.0

Ring Count 9.0

Amide Bonds 69.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0051843 VERIFIED: NO

Provenance & Taxonomy

OrganismPaenibacillus sp. sptzw28 [Bacterium]

FamilyBacteriocin

Tax ID715179

Structure & Mods

Confighead-to-tail cyclic bacteriocin scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsCyclized peptide scaffold annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Non-hemolytic Non-ribosomal