Peptide Database

Peptide NameCecropin B

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC176H300N52O43S

DescriptionStandard

        RWKVFKKIEKMGRNVRDGIIKAGPAIAVLGEAKAL
    

Molecular Weight3864.65 Da

Isoelectric Point (pI)10.64

Net Charge (pH 7.0)5.76

Net Charge (pH 7.4) 5.54

Charge Density (pH 7.0) 0.1646

GRAVY Index-0.09

Hydrophobic Moment 0.89

Boman Index-0.03

Instability Index40.83

Aliphatic Index 106.00

Aromaticity 0.0571

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1556.53

LogP -10.38

H-bond Donors 55.0

H-bond Acceptors 50.0

Rotatable Bonds 136.0

Heavy Atoms 272.0

Ring Count 4.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0374242 VERIFIED: YES

Provenance & Taxonomy

OrganismTrichoplusia ni [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)