Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length157 amino acids

Chemical FormulaC786H1186N182O242S8

DescriptionStandard

        QGTVYPSGNHTGPSYVAAPFVIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNITIAEETCSYFNISTEIFGSIIPEVREYSVTPYPVMLKLMATEIPIISLQQDSFTVEIQGSMEVFAVLPDSSTQSLFTINMAANTSIAPNIFDQKLMGSLCLNR
    

Molecular Weight17313.42 Da

Isoelectric Point (pI)4.07

Net Charge (pH 7.0)-10.15

Net Charge (pH 7.4) -10.47

Charge Density (pH 7.0) -0.0647

GRAVY Index0.22

Hydrophobic Moment 0.51

Boman Index0.23

Instability Index51.31

Aliphatic Index 83.89

Aromaticity 0.1338

Extinction Coeff. Reduced 13410.00

Extinction Coeff. Oxidized 13535.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6717.52

LogP -65.45

H-bond Donors 229.0

H-bond Acceptors 241.0

Rotatable Bonds 547.0

Heavy Atoms 1218.0

Ring Count 32.0

Amide Bonds 171.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0012070 VERIFIED: NO

Provenance & Taxonomy

OrganismTricholaema leucomelas [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria