Peptide Database

Peptide NameDermaseptin-PS1

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC379H601N99O125S3

DescriptionStandard

        MAFLKKSLFLVLFLGLISLSFCEEEKRENEDEEEQEDDEQSEEKRGLWKSLFKNVGKAAGKAALNAVTDMVNQGEQ
    

Molecular Weight8640.61 Da

Isoelectric Point (pI)4.53

Net Charge (pH 7.0)-7.48

Net Charge (pH 7.4) -7.74

Charge Density (pH 7.0) -0.0984

GRAVY Index-0.59

Hydrophobic Moment 0.67

Boman Index-0.09

Instability Index57.49

Aliphatic Index 79.61

Aromaticity 0.0789

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3693.77

LogP -34.86

H-bond Donors 124.0

H-bond Acceptors 121.0

Rotatable Bonds 309.0

Heavy Atoms 606.0

Ring Count 7.0

Amide Bonds 83.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0180717 VERIFIED: NO

Provenance & Taxonomy

OrganismPhyllomedusa sauvagei [Bacterium]

FamilyFrog skin active peptide (FSAP) family; Dermaseptin subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Amphibian defense peptide Non-hemolytic Non-ribosomal