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MYP_159680
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Basic Information
Defensin Pp, PopuDef
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
44 amino acids
C202H303N53O59S7
Standard
Sequence
GASPALWGCDSFLGYCRIACFAHEASVGQKDCAEGMICCLPNVF
Physicochemical Analysis
4642.34 Da
4.75
-2.21
-2.55
-0.0501
0.51
0.42
0.26
46.94
71.14
0.1136
6990.00
7365.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1745.73
-17.04
65.0
65.0
144.0
321.0
9.0
45.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0137863 VERIFIED: YES
Provenance & Taxonomy
Polypedates puerensis [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
17.3 μM
MIC
PaperThe first anionic defensin from amphibians.
RECORD: Rec_0219722 VERIFIED: YES
Provenance & Taxonomy
Polypedates puerensis [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
17.25 μM
MIC
RECORD: Rec_0241384 VERIFIED: YES
Provenance & Taxonomy
Polypedates puerensis [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus subtilis ATCC 6633
43.14 μM
MIC
PMID25792112 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25792112/
RECORD: Rec_0241603 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0264293 VERIFIED: YES
Provenance & Taxonomy
Polypedates puerensis [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
38.82 μM
MIC
PMID25792112 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25792112/
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