Peptide Database

Peptide NameSLAY-screened peptide P4016

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC59H90N16O21S2

DescriptionStandard

        SAHTTNMTCPVFD
    

Molecular Weight1423.57 Da

Isoelectric Point (pI)5.31

Net Charge (pH 7.0)-1.46

Net Charge (pH 7.4) -1.73

Charge Density (pH 7.0) -0.1122

GRAVY Index-0.12

Hydrophobic Moment 0.27

Boman Index0.12

Instability Index22.25

Aliphatic Index 30.00

Aromaticity 0.0769

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 593.72

LogP -8.23

H-bond Donors 21.0

H-bond Acceptors 23.0

Rotatable Bonds 41.0

Heavy Atoms 98.0

Ring Count 3.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0097294 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/