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MYP_159669
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Basic Information
[R/K]cTI
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
18 amino acids
C101H157N25O21S4
Standard
Sequence
KWCFKVCYKGICYKKCKG
Physicochemical Analysis
2185.74 Da
9.51
5.71
5.44
0.3174
-0.34
0.48
-0.11
-17.77
37.78
0.2222
8480.00
8730.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
770.39
-3.04
32.0
31.0
74.0
151.0
5.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0206988 VERIFIED: YES
Provenance & Taxonomy
host defense peptide from the horseshoe crab Tachypleus tridentatus [other]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 31714739 PMID31714739 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31714739/
RECORD: Rec_0214449 VERIFIED: YES
Provenance & Taxonomy
host defense peptide from the horseshoe crab Tachypleus tridentatus [other]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
HeLa
13.4±1.9 μM
CC50
PaperPubMed PMID: 31714739 PMID31714739 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31714739/
RECORD: Rec_0222688 VERIFIED: YES
Provenance & Taxonomy
host defense peptide from the horseshoe crab Tachypleus tridentatus [other]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human RBCs
32 μM
CC50
PaperPubMed PMID: 31714739 PMID31714739 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31714739/
RECORD: Rec_0379663 VERIFIED: YES
Provenance & Taxonomy
host defense peptide from the horseshoe crab Tachypleus tridentatus [other]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
2.5±0.1 μM
CC50
PaperPubMed PMID: 31714739 PMID31714739 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31714739/
RECORD: Rec_0380091 VERIFIED: YES
Provenance & Taxonomy
host defense peptide from the horseshoe crab Tachypleus tridentatus [other]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
4.3±0.3 μM
CC50
PaperPubMed PMID: 31714739 PMID31714739 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31714739/
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