‹ ›
MYP_159613
← PREVIOUS NEXT → BACK
Basic Information
D-Brevinin CTcu5 (11-21)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
21 amino acids
C103H178N28O24S2
Standard
Sequence
LIAGLAANFLPQILCKIARKC
Physicochemical Analysis
2256.82 Da
9.50
2.74
2.50
0.1304
1.07
0.74
0.29
25.84
149.05
0.0476
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
836.65
-4.60
30.0
29.0
75.0
157.0
2.0
22.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0107803 VERIFIED: YES
Provenance & Taxonomy
Clinotarsus curtipes [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
15-21
Bio-Activity Profile
Antimicrobial
B. coagulans ATCC 7050
6.25 μg/mL
MIC
PaperNovel antibacterial peptides from the skin secretion of the Indian bicoloured frog Clinotarsus curtipes.
RECORD: Rec_0108844 VERIFIED: YES
Provenance & Taxonomy
Clinotarsus curtipes,Odorrana andersonii,Odorrana grahami [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa ATCC 27853
100 μg/mL
MIC
PMID24161537;25997127;32679168 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24161537/
RECORD: Rec_0201689 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
all-D amino-acid peptide [D]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 25997127 PMID25997127 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25997127/
RECORD: Rec_0210354 VERIFIED: YES
Provenance & Taxonomy
Clinotarsus curtipes,Odorrana andersonii,Odorrana grahami [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus subtilis MTCC 14416
50 μg/mL
MIC
PMID24161537;25997127;32679168 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24161537/
RECORD: Rec_0212265 VERIFIED: YES
Provenance & Taxonomy
Odorrana grahami [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
FIRST PREV 1 2 3 4 5 ... 7 NEXT LAST
Showing 5 records on this page · Page 3 of 7