Peptide Database

Peptide NameImiglucerase

Function Ontology

Therapeutic / Biomedical activity ▸ Enzyme replacement therapy

Standard StatusStandard

Sequence Length497 amino acids

Chemical FormulaC2532H3854N672O711S16

DescriptionStandard

        ARPCIPKSFGYSSVVCVCNATYCDSFDPPTFPALGTFSRYESTRSGRRMELSMGPIQANHTGTGLLLTLQPEQKFQKVKGFGGAMTDAAALNILALSPPAQNLLLKSYFSEEGIGYNIIRVPMASCDFSIRTYTYADTPDDFQLHNFSLPEEDTKLKIPLIHRALQLAQRPVSLLASPWTSPTWLKTNGAVNGKGSLKGQPGDIYHQTWARYFVKFLDAYAEHKLQFWAVTAENEPSAGLLSGYPFQCLGFTPEHQRDFIARDLGPTLANSTHHNVRLLMLDDQRLLLPHWAKVVLTDPEAAKYVHGIAVHWYLDFLAPAKATLGETHRLFPNTMLFASEACVGSKFWEQSVRLGSWDRGMQYSHSIITNLLYHVVGWTDWNLALNPEGGPNWVRNFVDSPIIVDITKDTFYKQPMFYHLGHFSKFIPEGSQRVGLVASQKNDLDAVALMHPDGSAVVVVLNRSSKDVPLTIKDPAVGFLETISPGYSIHTYLWRRQ
    

Molecular Weight55596.80 Da

Isoelectric Point (pI)7.41

Net Charge (pH 7.0)1.33

Net Charge (pH 7.4) 0.02

Charge Density (pH 7.0) 0.0027

GRAVY Index-0.17

Hydrophobic Moment 0.76

Boman Index0.09

Instability Index36.90

Aliphatic Index 84.21

Aromaticity 0.1147

Extinction Coeff. Reduced 94310.00

Extinction Coeff. Oxidized 94685.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0143040 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyEnzyme

Tax ID9606

Structure & Mods

Configsingle-chain therapeutic peptide/protein [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsLipidation

Bio-Activity Profile

Function

Enzyme replacement

Half-Life0.06-0.173 hours

RECORD: Rec_0289817 VERIFIED: NO