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MYP_159546
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Basic Information
P1
Antimicrobial
Antiviral
Antiviral ▸ Anti-Influenza virus
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Standard
9 amino acids
C42H68N14O15S2
Standard
Sequence
CNDFRSKTC
Physicochemical Analysis
1073.20 Da
8.06
0.74
0.51
0.0823
-1.01
0.20
-0.46
49.33
0.00
0.1111
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
504.89
-7.51
20.0
18.0
35.0
73.0
1.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0068766 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-Influenza virus Replication inhibition
Avian influenza viruss (AIV) H9N2 | MDCK cells
50 μM
% inhibition
Mammalian: 1.2 h; Yeast: >20 h; E. coli: >10 h
PaperA novel peptide inhibits the influenza virus replication by preventing the viral attachment to the host cells. | Rajik M, Omar AR, Ideris A, Hassan SS, Yusoff K. | Int J Biol Sci. 2009 Aug 8;5(6):543-8. | DOI:10.7150/ijbs.5.543 | PMID:19680476 PMID19680476 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19680476/
RECORD: Rec_0208493 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
Evidence URLhttps://patents.google.com/patent/US20110135676A1/en PatentUS 2011/0135676 A1
RECORD: Rec_0242184 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Library-derived peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor
Avian influenza virus (Virus entry); MDCK
48 μM
Yeast two-hybrid assay
PaperIdentification and characterisation of a novel anti-viral peptide against avian influenza virus H9N2. | Rajik M, Jahanshiri F, Omar AR, Ideris A, Hassan SS, Yusoff K. | Virol J. 2009 | PMID:19497129 PMID19497129 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19497129/
RECORD: Rec_0292202 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 55.6%, C 44.4% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0357168 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Replication inhibitor
Avian influenza virus (Replication); MDCK
53 %
Flow cytometry
PaperA novel peptide inhibits the influenza virus replication by preventing the viral attachment to the host cells. | Rajik M, Omar AR, Ideris A, Hassan SS, Yusoff K. | Int J Biol Sci. 2009 | PMID:19680476 PMID19680476 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19680476/