Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC386H630N102O104S10

DescriptionStandard

        MKFLFLFLAILLAMEPVVSEEECWMKGKCRLVCKNDEDSVTRCSNRKRCCILSRYLTIVPMTIDRILPWTTPQV
    

Molecular Weight8684.40 Da

Isoelectric Point (pI)8.62

Net Charge (pH 7.0)2.45

Net Charge (pH 7.4) 2.13

Charge Density (pH 7.0) 0.0331

GRAVY Index0.20

Hydrophobic Moment 0.50

Boman Index0.03

Instability Index55.18

Aliphatic Index 100.00

Aromaticity 0.0811

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3315.51

LogP -23.36

H-bond Donors 123.0

H-bond Acceptors 117.0

Rotatable Bonds 288.0

Heavy Atoms 602.0

Ring Count 12.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0047848 VERIFIED: NO

Provenance & Taxonomy

OrganismBos mutus [Animal]

FamilyDefensin

Tax ID30521

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence