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MYP_159504
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Basic Information
[Aib2]PACAP38
Neuroprotective
not Standard
38 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
HXDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNK
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0318111 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
PACAP
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
Amidation
Aib residue
Bio-Activity Profile
Neuroprotective
0.0071±0.0014 μM
IC50
DPP IV, in vitro; 3900 s
PaperNovel stable PACAP analogs with potent activity towards the PAC1 receptor PMID18353507 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18353507/