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MYP_159493
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Basic Information
Decoralin [AC3]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
11 amino acids
C66H126N16O12
Standard
Sequence
LLLLLIRKLIK
Physicochemical Analysis
1335.81 Da
11.17
2.76
2.55
0.2507
1.77
0.61
0.33
-6.35
283.64
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
468.26
2.14
17.0
15.0
49.0
94.0
0.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0009493 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Jurkat
25±1 μM
EC50
PaperMultidimensional Design of Anticancer Peptides. Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10370-10374. doi: 10.1002/anie.201504018. PMID: 26119906. PMID26119906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26119906/
RECORD: Rec_0103638 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
A549
22±1 μM
EC50
PaperMultidimensional Design of Anticancer Peptides. Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10370-10374. doi: 10.1002/anie.201504018. PMID: 26119906. PMID26119906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26119906/
RECORD: Rec_0187234 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0215352 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
HDMEC
125-250 μM
EC50
PaperMultidimensional Design of Anticancer Peptides. Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10370-10374. doi: 10.1002/anie.201504018. PMID: 26119906. PMID26119906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26119906/
RECORD: Rec_0226127 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperMultidimensional Design of Anticancer Peptides. Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10370-10374. doi: 10.1002/anie.201504018. PMID: 26119906. PMID26119906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26119906/
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