Peptide Database

Peptide NameHepcidin-2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length91 amino acids

Chemical FormulaC459H731N131O130S11

DescriptionStandard

        MKLSNVFLAAVVILTCVCVFQITAVPFIQQVQDEHHVESEELQENQHLTEAEHRLTDPLVLFRTKRQSHLSLCRFCCKCCRNKGCGYCCKF
    

Molecular Weight10517.23 Da

Isoelectric Point (pI)7.55

Net Charge (pH 7.0)0.85

Net Charge (pH 7.4) 0.22

Charge Density (pH 7.0) 0.0094

GRAVY Index0.04

Hydrophobic Moment 0.72

Boman Index0.01

Instability Index42.82

Aliphatic Index 88.79

Aromaticity 0.0769

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 2115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4216.64

LogP -39.50

H-bond Donors 154.0

H-bond Acceptors 147.0

Rotatable Bonds 352.0

Heavy Atoms 731.0

Ring Count 14.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0394078 VERIFIED: YES

Provenance & Taxonomy

OrganismDanio rerio [Animal]

FamilyHepcidin

Tax ID7955

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic

TargetNo Target Organism Found