Peptide Database

Peptide NameDEFB120

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC136H227N49O42S6

DescriptionStandard

        QCWKDGHCRLVCKDSEDSVIRCANRKRCC
    

Molecular Weight3412.95 Da

Isoelectric Point (pI)8.68

Net Charge (pH 7.0)2.79

Net Charge (pH 7.4) 2.44

Charge Density (pH 7.0) 0.0962

GRAVY Index-0.80

Hydrophobic Moment 0.63

Boman Index-0.42

Instability Index53.03

Aliphatic Index 50.34

Aromaticity 0.0345

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1524.09

LogP -18.85

H-bond Donors 61.0

H-bond Acceptors 52.0

Rotatable Bonds 117.0

Heavy Atoms 233.0

Ring Count 3.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0213924 VERIFIED: YES

Provenance & Taxonomy

OrganismDipodomys ordii [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)