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MYP_159433
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Basic Information
Chemokinostatin-1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Anti-angiogenic
Standard
24 amino acids
C114H202N34O32S2
Standard
Sequence
NGRKACLNPASPIVKKIIEKMLNS
Physicochemical Analysis
2625.16 Da
10.03
3.75
3.52
0.1562
-0.25
0.67
-0.07
78.40
101.67
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1088.05
-10.94
37.0
38.0
91.0
182.0
2.0
26.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0055602 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID18307172 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18307172/
RECORD: Rec_0087633 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Chemokinostatin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-angiogenic
Endothelial cells
Endothelial migration assay
PaperNovel anti-angiogenic peptides derived from ELR-containing CXC chemokines PMID18307172 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18307172/
RECORD: Rec_0116853 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0146319 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Chemokinostatin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-angiogenic
Endothelial cells
Endothelial proliferation assay
PaperNovel anti-angiogenic peptides derived from ELR-containing CXC chemokines PMID18307172 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18307172/
RECORD: Rec_0204089 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID18307172 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18307172/
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