Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length448 amino acids

Chemical FormulaC2212H3493N613O623S9

DescriptionStandard

        TNPGFVVRITQAGLDYARQHGVAVLEQELHQLQLPDISGEFRVRRVGKVHYELSRLNLRSFRLPSSQISPIPNVGLQVSISGAFAELDGNWRVKVHFIRDHGSFDLKVEGLSIGIDLKLGTDGSGKPTADVSDCSAHVSSVRVHFSGKFSWLYNLFHSAVESVFRRSLESKVCEQVVSSVHSELQSYLGTLPVTAKIDAVAGIDYALVAPPVAAAQALDAELKGEFFSLAHRSAVPFSPAPLALPPDHARMVYFGASSYFFNTAGLVYHTAGALVFELTDSMIPKGLDFHLNTSTFSAFVPQLEERYPDMLMKLRLSTPAAPFLSIGPEGLSLRPVVDIQAYAILPSSSLAPLFLLNLGQSSPCVLAEPPGRSAASRRLCRLRLSLKHSDVGPFQVRTLQSVMNILASSILLPRVNARLAQGFPLPLLRRTQLSNVLVQWHQVSARPR
    

Molecular Weight48930.71 Da

Isoelectric Point (pI)9.26

Net Charge (pH 7.0)7.71

Net Charge (pH 7.4) 6.63

Charge Density (pH 7.0) 0.0172

GRAVY Index0.11

Hydrophobic Moment 0.70

Boman Index0.10

Instability Index47.27

Aliphatic Index 101.63

Aromaticity 0.0826

Extinction Coeff. Reduced 31400.00

Extinction Coeff. Oxidized 31650.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0313152 VERIFIED: NO

Provenance & Taxonomy

OrganismNothoprocta pentlandii [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria