Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length130 amino acids

Chemical FormulaC611H996N198O181S9

DescriptionStandard

        MKTFLLICAVLFSLAPGRSDLEVDRVCGYGTARCRRKCKSQERKISRCPNTYTCCLKAWAYSSLNINRPSLQGRPPEPSGSPEQPGARSGRQRGLLSSSGQSHHPRGRPWSTGSRLRPPACSLLDLGVEQ
    

Molecular Weight14300.25 Da

Isoelectric Point (pI)10.09

Net Charge (pH 7.0)12.60

Net Charge (pH 7.4) 12.15

Charge Density (pH 7.0) 0.0970

GRAVY Index-0.62

Hydrophobic Moment 0.69

Boman Index-0.18

Instability Index66.68

Aliphatic Index 65.31

Aromaticity 0.0538

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6113.14

LogP -77.37

H-bond Donors 226.0

H-bond Acceptors 205.0

Rotatable Bonds 465.0

Heavy Atoms 999.0

Ring Count 23.0

Amide Bonds 138.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0043935 VERIFIED: NO

Provenance & Taxonomy

OrganismFukomys damarensis [Animal]

FamilyBeta-defensin; Defensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic