Peptide Database

Peptide NameCecropin A

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC193H328N56O43

DescriptionStandard

        RWKLFKKIEKVGRKVRDGLIKAGPAIAVIGQAKFIGK
    

Molecular Weight4121.02 Da

Isoelectric Point (pI)11.24

Net Charge (pH 7.0)8.76

Net Charge (pH 7.4) 8.54

Charge Density (pH 7.0) 0.2366

GRAVY Index-0.11

Hydrophobic Moment 0.91

Boman Index-0.04

Instability Index22.17

Aliphatic Index 108.11

Aromaticity 0.0811

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1629.47

LogP -9.48

H-bond Donors 58.0

H-bond Acceptors 52.0

Rotatable Bonds 147.0

Heavy Atoms 292.0

Ring Count 5.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0068785 VERIFIED: YES

Provenance & Taxonomy

OrganismBombyx mori [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)