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MYP_159332
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Basic Information
c2
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
6 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
KWXWKK
Physicochemical Analysis
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0024262 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
Lactam
Lactam
X=2-Nal-CH2-
Bio-Activity Profile
Antimicrobial Anticancer
Ramos
8±1 μM
IC50
PaperPubMed PMID: 22933412 PMID22933412 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22933412/
RECORD: Rec_0142147 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
Lactam
Lactam
X=2-Nal-CH2-
Bio-Activity Profile
Antimicrobial Anticancer
Ramos
7.9±0.3 μM
IC50
PaperPubMed PMID: 22933412 PMID22933412 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22933412/
RECORD: Rec_0151008 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
Lactam
Lactam
X=2-Nal-CH2-
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human red blood cells
31 μM
EC50
PaperPubMed PMID: 22933412 PMID22933412 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22933412/
RECORD: Rec_0183485 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
Lactam
Lactam
X=2-Nal-CH2-
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
MRC-5
13±1 μM
IC50
PaperPubMed PMID: 22933412 PMID22933412 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22933412/
RECORD: Rec_0189213 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
Lactam
Lactam
X=p-CF3-Bzl-
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human red blood cells
36 μM
EC50
PaperPubMed PMID: 22933412 PMID22933412 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22933412/
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