Peptide Database

Peptide NameTransforming growth factor alpha

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length50 amino acids

Chemical FormulaC239H354N70O72S6

DescriptionStandard

        VVSHFNDCPDSHTQFCFHGTCRFLVQEDKPACVCHSGYVGARCEHADLLA
    

Molecular Weight5552.18 Da

Isoelectric Point (pI)5.85

Net Charge (pH 7.0)-2.88

Net Charge (pH 7.4) -3.44

Charge Density (pH 7.0) -0.0576

GRAVY Index-0.08

Hydrophobic Moment 0.46

Boman Index0.05

Instability Index19.48

Aliphatic Index 60.40

Aromaticity 0.1000

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2239.31

LogP -24.69

H-bond Donors 82.0

H-bond Acceptors 80.0

Rotatable Bonds 173.0

Heavy Atoms 387.0

Ring Count 12.0

Amide Bonds 52.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0162684 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide8-21; 16-32; 34-43

Bio-Activity Profile

Function

Cytokine Growth factor Growth factor signaling

RECORD: Rec_0329842 VERIFIED: NO