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MYP_159311
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Basic Information
D-Apidaecin-1B [1Orn,10 R], D-Api88
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxicity
not Standard
18 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XNNRPVYIPRPRPPHPRL
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0077302 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
unspecified non-canonical residue at 1
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli DSM 10233
64 μg/mL
MIC
PMID27285299;22594381 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27285299/
RECORD: Rec_0081823 VERIFIED: YES
Provenance & Taxonomy
Apis mellifera [Animal]
7460
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Gu (N
L-Ornithine at 1; L-Ornithine
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Klebsiella pneumoniae ATCC 10031
4 μg/mL
MIC
PMID29309652 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29309652/
RECORD: Rec_0087992 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
unspecified non-canonical residue at 1
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli BW25113 del-sbmA+psbmA
4 μg/mL
MIC
PMID27285299;22594381 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27285299/
RECORD: Rec_0088857 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
unspecified non-canonical residue at 1
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli D31
1 μg/mL
MIC
PMID27285299;22594381 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27285299/
RECORD: Rec_0089439 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
unspecified non-canonical residue at 1
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli BL21AI
32 μg/mL
MIC
PMID27285299;22594381 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27285299/
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