MYP_159311
Basic Information
D-Apidaecin-1B [1Orn,10 R], D-Api88
Anticancer
Anticancer Cytotoxic anticancer activity Cytotoxic
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antibacterial Anti-Gram-negative
Antimicrobial Antibacterial Anti-Gram-positive
Antimicrobial Antibacterial Anti-Mycobacterium
Delivery / Targeting Barrier transport Blood-brain barrier shuttle Blood-Brain Barrier
Delivery / Targeting Drug delivery vehicle
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Toxicity / Safety Cytotoxicity
Toxicity / Safety Cytotoxicity Cytotoxic
Venom / Toxin General toxin Cytotoxic
Venom / Toxin General toxin Cytotoxicity
not Standard
18 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XNNRPVYIPRPRPPHPRL
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0331850 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic designed peptide
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Acetylation
Amidation
Non-standard residues/chemistry in sequence: ONNRPVYIPRPRPPHPRL
Bio-Activity Profile
Antimicrobial Antimycobacterial
Mycobacterium vaccae
MIC
RECORD: Rec_0332338 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
unspecified non-canonical residue at 1
Bio-Activity Profile
Antimicrobial Antibacterial
Salmonella typhi S5
0.125 μg/mL
MIC
RECORD: Rec_0332908 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
unspecified non-canonical residue at 1
Bio-Activity Profile
Antimicrobial Antibacterial
Klebsiella pneumoniae 123132
2 μg/mL
MIC
RECORD: Rec_0332916 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
unspecified non-canonical residue at 1
Bio-Activity Profile
Antimicrobial Antibacterial
Micrococcus luteus ATCC 10240
1.95 μg/mL
MIC
RECORD: Rec_0333536 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Guan
Amidation
Bio-Activity Profile
Drug Delivery Vehicle Blood-Brain Barrier
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