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MYP_159285
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Basic Information
CPF-MW2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
28 amino acids
C129H215N35O35S2
Standard
Sequence
GLGSLLGKAFKFGLKTVGKMMGGAPREE
Physicochemical Analysis
2880.43 Da
10.00
2.77
2.55
0.0988
-0.02
0.57
0.12
19.96
73.21
0.0714
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1121.27
-9.83
39.0
40.0
101.0
201.0
3.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0043606 VERIFIED: YES
Provenance & Taxonomy
Xenopus muelleri [Animal]
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID21664395 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21664395/
RECORD: Rec_0062767 VERIFIED: YES
Provenance & Taxonomy
Xenopus muelleri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
6 μM
MIC
PaperPeptidomic analysis of skin secretions demonstrates that the allopatric populations of Xenopus muelleri (Pipidae) are not conspecific
RECORD: Rec_0063928 VERIFIED: YES
Provenance & Taxonomy
Xenopus muelleri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Hemolytic Anti-Gram-positive
Staphylococcus aureus
6 μM
MIC
RECORD: Rec_0108817 VERIFIED: YES
Provenance & Taxonomy
Xenopus muelleri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Hemolytic
Hemolytic activity
105 μM
LC50
RECORD: Rec_0150931 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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