Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length182 amino acids

Chemical FormulaC887H1397N241O243S5

DescriptionStandard

        PVALPVAQEPMLLVAVTDFVANSAAFAYFTAGALRRNISSATVLQRFPLQLKTKSFGIFTPQLQEHFPDQPMELQVWARRQPLFSCHPDAVHGALFGSAEAFVLLPNGTRVPAFLLDIDANVTGKPIITGNRLGATISLKGGSWGCCGPVPGSGLPVPQVQRLETLLNLGLRLFGVPRANSE
    

Molecular Weight19485.37 Da

Isoelectric Point (pI)9.07

Net Charge (pH 7.0)3.21

Net Charge (pH 7.4) 2.94

Charge Density (pH 7.0) 0.0177

GRAVY Index0.22

Hydrophobic Moment 0.59

Boman Index0.18

Instability Index44.08

Aliphatic Index 98.63

Aromaticity 0.0824

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7584.15

LogP -84.18

H-bond Donors 258.0

H-bond Acceptors 254.0

Rotatable Bonds 615.0

Heavy Atoms 1376.0

Ring Count 37.0

Amide Bonds 198.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0282335 VERIFIED: NO

Provenance & Taxonomy

OrganismProbosciger aterrimus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria