Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length64 amino acids

Chemical FormulaC319H520N94O85S9

DescriptionStandard

        LGAAEGHCFNLSGVCRRDVCKVVEDQIGACRRRMKCCRAWWILMPIPTPLTMSDYQEPLKPKLK
    

Molecular Weight7320.71 Da

Isoelectric Point (pI)9.10

Net Charge (pH 7.0)4.79

Net Charge (pH 7.4) 4.44

Charge Density (pH 7.0) 0.0749

GRAVY Index-0.20

Hydrophobic Moment 0.66

Boman Index-0.07

Instability Index59.74

Aliphatic Index 79.22

Aromaticity 0.0625

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2868.65

LogP -24.05

H-bond Donors 106.0

H-bond Acceptors 100.0

Rotatable Bonds 240.0

Heavy Atoms 507.0

Ring Count 12.0

Amide Bonds 66.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0070078 VERIFIED: NO

Provenance & Taxonomy

OrganismPiliocolobus tephrosceles [Animal]

FamilyDefensin

Tax ID591936

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal