Peptide Database

Peptide NameHepcidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC442H704N124O134S13

DescriptionStandard

        MKAFSIAVAVTLVLAFLCILESSAVPFAGVQMQELEETGSNDTPVEAHQGGETSLDSWMMSDHIRKKRNSHISLCVWCCNCCRNQKGCGICCKF
    

Molecular Weight10315.91 Da

Isoelectric Point (pI)6.25

Net Charge (pH 7.0)-1.31

Net Charge (pH 7.4) -1.83

Charge Density (pH 7.0) -0.0140

GRAVY Index0.14

Hydrophobic Moment 0.38

Boman Index0.10

Instability Index43.77

Aliphatic Index 78.83

Aromaticity 0.0638

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4128.87

LogP -44.67

H-bond Donors 151.0

H-bond Acceptors 149.0

Rotatable Bonds 344.0

Heavy Atoms 713.0

Ring Count 13.0

Amide Bonds 101.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0342234 VERIFIED: NO

Provenance & Taxonomy

OrganismGouania willdenowi [Animal]

FamilyHepcidin

Tax ID441366

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal